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New hope for kids with severe bowel disease: drug trial launches

NCT ID NCT07158242

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 27 times

Summary

This study tests a new medicine called afimkibart in children aged 2 to 17 with moderate to severe ulcerative colitis, a condition causing inflammation and sores in the colon. The goal is to see if the drug can safely reduce symptoms and help children reach remission (feeling better with less inflammation). About 100 children will take part, and the study lasts up to 52 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Addenbrooke's Hospital

    RECRUITING

    Cambridge, CB2 0QQ, United Kingdom

  • Birmingham Children's Hospital

    RECRUITING

    Birmingham, B4 6NH, United Kingdom

  • Children's Healthcare of Atlanta

    RECRUITING

    Atlanta, Georgia, 30342, United States

  • Children's Hospital ZheJiang University School of Medicine

    RECRUITING

    Hangzhou, Zhejiang, 310052, China

  • Chulalongkorn University

    RECRUITING

    Bangkok, 10330, Thailand

  • NYU Langone Health

    RECRUITING

    New York, New York, 10016, United States

  • National Taiwan University Hospital

    RECRUITING

    Taipei, 100, Taiwan

  • Perth Children's Hospital

    RECRUITING

    Nedlands, Western Australia, 6009, Australia

  • Ramathibodi Hospital

    RECRUITING

    Bangkok, Thailand

  • Royal Children's Hospital

    RECRUITING

    Parkville, Victoria, 3052, Australia

  • Sheffield Childrens Hospital

    RECRUITING

    Sheffield, S10 2TH, United Kingdom

  • Siriraj Hospital

    RECRUITING

    Bangkok, 10700, Thailand

Conditions

Explore the condition pages connected to this study.