New hope for kids with severe gut disease: drug trial launches
NCT ID NCT07158242
First seen Jun 27, 2026 · Last updated Jul 17, 2026 · Updated 2 times
Summary
This study tests a new medicine called afimkibart in children aged 2 to 17 with moderate to severe ulcerative colitis, a disease that causes inflammation and sores in the colon. The goal is to see if the drug can safely help children feel better and achieve remission (no symptoms) at 12 and 52 weeks. About 100 children who have not responded well to other treatments will take part.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Addenbrooke's Hospital
RECRUITINGCambridge, CB2 0QQ, United Kingdom
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Birmingham Children's Hospital
RECRUITINGBirmingham, B4 6NH, United Kingdom
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Children's Healthcare of Atlanta
RECRUITINGAtlanta, Georgia, 30342, United States
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Children's Hospital ZheJiang University School of Medicine
RECRUITINGHangzhou, Zhejiang, 310052, China
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Chulalongkorn University
RECRUITINGBangkok, 10330, Thailand
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Emmed Research
RECRUITINGPretoria, 0002, South Africa
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Mater Hospital Brisbane
RECRUITINGSouth Brisbane, Queensland, 4101, Australia
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NYU Langone Health
RECRUITINGNew York, New York, 10016, United States
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National Taiwan University Hospital
RECRUITINGTaipei, 100, Taiwan
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Perth Children's Hospital
RECRUITINGNedlands, Western Australia, 6009, Australia
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Ramathibodi Hospital
RECRUITINGBangkok, Thailand
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Royal Children's Hospital
RECRUITINGParkville, Victoria, 3052, Australia
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Sheffield Childrens Hospital
RECRUITINGSheffield, S10 2TH, United Kingdom
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Siriraj Hospital
RECRUITINGBangkok, 10700, Thailand
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University of South Florida
RECRUITINGTampa, Florida, 33612, United States
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