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New lupus drug shows promise in Mid-Stage trial

NCT ID NCT04895696

Ongoing Disease control Sponsor: Bristol-Myers Squibb Source: ClinicalTrials.gov ↗

First seen May 16, 2026 · Last updated May 23, 2026 · Updated 1 time

Summary

This study tests a new drug, afimetoran, to see if it can safely control active lupus better than a placebo. About 268 adults with lupus will take either the drug or a placebo for 48 weeks. The goal is to reduce lupus symptoms and disease activity, with an option for placebo patients to switch to the drug later.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Local Institution - 0001

    Barranquilla, 080020, Colombia

  • Local Institution - 0003

    Zipaquirá, 250252, Colombia

  • Local Institution - 0004

    Bogotá, 110221, Colombia

  • Local Institution - 0005

    Chía, 250001, Colombia

  • Local Institution - 0006

    Salvador, Estado de Bahia, 40150-150, Brazil

  • Local Institution - 0007

    Porto Alegre, Rio Grande do Sul, 90480-000, Brazil

  • Local Institution - 0008

    Juiz de Fora, Minas Gerais, 36010-570, Brazil

  • Local Institution - 0009

    São Paulo, 04266-010, Brazil

  • Local Institution - 0010

    Curitiba, Paraná, 80030110, Brazil

  • Local Institution - 0014

    São Bernardo do Campo, São Paulo, 09715-090, Brazil

  • Local Institution - 0017

    Guadalajara, Jalisco, 44650, Mexico

  • Local Institution - 0018

    Mexico City, Mexico City, 11850, Mexico

  • Local Institution - 0020

    León, Guanajuato, 37000, Mexico

  • Local Institution - 0021

    Chihuahua City, 31210, Mexico

  • Local Institution - 0022

    Zapopan, Jalisco, 45070, Mexico

  • Local Institution - 0025

    Córdoba, Córdoba Province, 5004, Argentina

  • Local Institution - 0027

    San Miguel de Tucumán, Tucumán Province, T4000, Argentina

  • Local Institution - 0029

    Mesquite, Texas, 75150, United States

  • Local Institution - 0031

    Salvador, Estado de Bahia, 41820-020, Brazil

  • Local Institution - 0037

    San Juan, 00917, Puerto Rico

  • Local Institution - 0040

    CABA, Distrito Federal, 1406, Argentina

  • Local Institution - 0041

    San Juan, 5400, Argentina

  • Local Institution - 0042

    Middleburg Heights, Ohio, 44130, United States

  • Local Institution - 0043

    Santiago, Santiago Metropolitan, 7501126, Chile

  • Local Institution - 0044

    Strasbourg, 67098, France

  • Local Institution - 0045

    São José do Rio Preto, São Paulo, 15090000, Brazil

  • Local Institution - 0048

    Bordeaux, 33076, France

  • Local Institution - 0049

    Poznan, 60-218, Poland

  • Local Institution - 0052

    Wroclaw, 50-556, Poland

  • Local Institution - 0055

    Madrid, 28009, Spain

  • Local Institution - 0056

    A Coruña, 15006, Spain

  • Local Institution - 0057

    Seville, 41014, Spain

  • Local Institution - 0058

    Barcelona, 08035, Spain

  • Local Institution - 0060

    Mexico City, Mexico City, 06760, Mexico

  • Local Institution - 0061

    Mérida, 97070, Mexico

  • Local Institution - 0062

    Camberwell, Victoria, 3124, Australia

  • Local Institution - 0063

    Botany, New South Wales, 2019, Australia

  • Local Institution - 0064

    Ivanhoe, Victoria, 3079, Australia

  • Local Institution - 0065

    Woodville, South Australia, 5011, Australia

  • Local Institution - 0066

    Maroochydore, Queensland, 4558, Australia

  • Local Institution - 0067

    Bucharest, 011172, Romania

  • Local Institution - 0068

    Giroc, 307220, Romania

  • Local Institution - 0070

    Eagan, Minnesota, 55121, United States

  • Local Institution - 0071

    Monterrey, Nuevo León, 64000, Mexico

  • Local Institution - 0072

    Westmead, New South Wales, 2145, Australia

  • Local Institution - 0073

    Santiago, Santiago Metropolitan, 0, Chile

  • Local Institution - 0074

    Buenos Aires, Distrito Federal, C1121ABE, Argentina

  • Local Institution - 0075

    Providencia, Santiago Metropolitan, 7500504, Chile

  • Local Institution - 0076

    Cali, 760042, Colombia

  • Local Institution - 0077

    Taipei, 11217, Taiwan

  • Local Institution - 0078

    Taichung, 407, Taiwan

  • Local Institution - 0079

    Taipei, 10002, Taiwan

  • Local Institution - 0080

    Kaohsiung Niao Sung Dist, 83301, Taiwan

  • Local Institution - 0081

    Taichung, 404, Taiwan

  • Local Institution - 0082

    Râmnicu Vâlcea, Vâlcea County, 247065, Romania

  • Local Institution - 0083

    Brest, Finistère, 29609, France

  • Local Institution - 0084

    Freiburg im Breisgau, 79106, Germany

  • Local Institution - 0085

    Berlin, 10117, Germany

  • Local Institution - 0086

    Essen, 45122, Germany

  • Local Institution - 0087

    Cologne, North Rhine-Westphalia, 50937, Germany

  • Local Institution - 0091

    Las Vegas, Nevada, 89128, United States

  • Local Institution - 0093

    Cuiabá, Mato Grosso, 78020-500, Brazil

  • Local Institution - 0095

    Kitakyushu, Fukuoka, 807-8556, Japan

  • Local Institution - 0096

    Sapporo, Hokkaido, 060-8648, Japan

  • Local Institution - 0097

    Tokyo, 104-8560, Japan

  • Local Institution - 0098

    Shinjuku-ku, Tokyo, 1600035, Japan

  • Local Institution - 0099

    Sendai, Miyagi, 980-8574, Japan

  • Local Institution - 0100

    Birmingham, Alabama, 35205, United States

  • Local Institution - 0103

    Charlotte, North Carolina, 28211, United States

  • Local Institution - 0104

    Kanazawa, Ishikawa-ken, 920-8641, Japan

  • Local Institution - 0105

    Shinjuku-ku, Tokyo, 1628655, Japan

  • Local Institution - 0106

    Dublin, D15 X40D, Ireland

  • Local Institution - 0107

    Galway, H91 TY80, Ireland

  • Local Institution - 0110

    Bradford, BD5 0NA, United Kingdom

  • Local Institution - 0111

    Cambridge, Cambridgeshire, CB2 2QQ, United Kingdom

  • Local Institution - 0112

    Marseille, 13003, France

  • Local Institution - 0113

    Itabashiku, Tokyo, 173-8610, Japan

  • Local Institution - 0114

    Eiheiji-cho,Yoshida-gun, Fukui, 910-1193, Japan

  • Local Institution - 0115

    Chiba, 260-8712, Japan

  • Local Institution - 0116

    Tokyo, 113-8654, Japan

  • Local Institution - 0117

    Bunkyo-ku, Tokyo, 1138431, Japan

  • Local Institution - 0119

    Manorhamilton, Leitrim, 0, Ireland

  • Local Institution - 0121

    Clearwater, Florida, 33765, United States

  • Local Institution - 0122

    Orlando, Florida, 32808, United States

  • Local Institution - 0123

    Huntington Beach, California, 92648, United States

  • Local Institution - 0124

    St Louis, Missouri, 63110, United States

  • Local Institution - 0125

    Manchester, M13 9WL, United Kingdom

  • Local Institution - 0127

    Osorno, Los Lagos Region, 5290000, Chile

  • Local Institution - 0128

    Buenos Aires, C1426ABP, Argentina

  • Local Institution - 0129

    Lille, 59037, France

  • Local Institution - 0130

    Quilmes, Buenos Aires, 1878, Argentina

  • Local Institution - 0132

    The Bronx, New York, 10461, United States

  • Local Institution - 0134

    Wheaton, Maryland, 20902, United States

  • Local Institution - 0136

    Amarillo, Texas, 79124, United States

  • Local Institution - 0137

    South Miami, Florida, 33143, United States

  • Local Institution - 0138

    Aichi, 457-8511, Japan

  • Local Institution - 0140

    Manhasset, New York, 11030, United States

  • Local Institution - 0143

    Valdivia, Los Ríos Region, 2279374, Chile

  • Local Institution - 0144

    Caen, 14033, France

  • Local Institution - 0146

    Orland Park, Illinois, 60467, United States

  • Local Institution - 0149

    Warsaw, 00-874, Poland

  • Local Institution - 0150

    Meguro-ku, Tokyo, 1538515, Japan

  • Local Institution - 0151

    Columbus, Ohio, 43203, United States

  • Local Institution - 0152

    Allen, Texas, 75013, United States

  • Local Institution - 0154

    Plantation, Florida, 33324, United States

  • Local Institution - 0155

    Tamarac, Florida, 33321, United States

  • Local Institution - 0156

    Pessac, Aquitaine, 33600, France

  • Local Institution - 0157

    Bucharest, 011053, Romania

  • Local Institution - 0158

    Mexico City, 14080, Mexico

  • Local Institution - 0159

    La Palma, California, 90623, United States

  • Local Institution - 0160

    Atlanta, Georgia, 30318, United States

  • Local Institution - 0162

    Fukushima, 960-1295, Japan

  • Local Institution - 0163

    San Antonio, Texas, 78215, United States

  • Local Institution - 0164

    Woodland Hills, California, 91364, United States

  • Local Institution - 0165

    St Louis, Missouri, 63141, United States

  • Local Institution - 0167

    Kissimmee, Florida, 34741, United States

  • Local Institution - 0170

    La Jolla, California, 92037, United States

  • Local Institution - 0171

    Baton Rouge, Louisiana, 70836, United States

  • Local Institution - 0172

    San Diego, California, 92128, United States

  • Local Institution - 0173

    Ormond Beach, Florida, 32174, United States

  • Local Institution - 0174

    Changchun, Jilin, 130000, China

  • Local Institution - 0176

    Nanjing, Jiangsu, 210000, China

  • Local Institution - 0177

    Beijing, Beijing Municipality, 100029, China

  • Local Institution - 0178

    Jinan, Shandong, 250012, China

  • Local Institution - 0179

    Dalian, Liaoning, 116023, China

  • Local Institution - 0180

    Beijing, Beijing Municipality, 100144, China

  • Local Institution - 0183

    Jining, Shandong, 272011, China

  • Local Institution - 0184

    Shenzhen, Guangdong, 518107, China

  • Local Institution - 0187

    Hopkinsville, Kentucky, 42240, United States

  • Local Institution - 0188

    Nanjing, Jiangsu, 210029, China

  • Local Institution - 0190

    Medellín, Antioquia, 050021, Colombia

  • Local Institution - 0193

    Suzhou, Jiangsu, 215006, China

  • Local Institution - 0195

    San Fernando, Buenos Aires, 1646, Argentina

  • Local Institution - 0197

    Allen, Texas, 75013, United States

  • Local Institution - 0203

    Charlotte, North Carolina, 28204, United States

  • Local Institution - 0204

    Warsaw, Masovian Voivodeship, 02-665, Poland

  • Local Institution - 0205

    Suwanee, Georgia, 30024, United States

  • Local Institution - 0206

    Santander, Cantabria, 39008, Spain

  • Local Institution - 0207

    Buenos Aires, 1425, Argentina

  • Local Institution - 0208

    New Delhi, National Capital Territory of Delhi, 110029, India

  • Local Institution - 0209

    Secunderabad, Telangana, 500003, India

  • Local Institution - 0210

    Bengaluru, Karnataka, 560010, India

  • Local Institution - 0214

    Gurugram, Haryana, 122001, India

  • Local Institution - 0218

    Fuchū, Tokyo, 1838524, Japan

  • Local Institution - 0219

    West Long Branch, New Jersey, 07764, United States

  • Local Institution - 0223

    Bellevue, Washington, 98004, United States

  • Local Institution - 0226

    Ahmedabad, Gujarat, 380015, India

Conditions

Explore the condition pages connected to this study.

SYSTEMIC LUPUS ERYTHEMATOSUS