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New hope for Hard-to-Treat cancers: targeted drug afatinib tested in Genetic-Mutation patients

NCT ID NCT06385483

First seen Oct 31, 2025 · Last updated Apr 30, 2026 · Updated 33 times

Summary

This study tests the drug afatinib in 19 patients with advanced solid tumors or lymphomas that have a specific EGFR gene mutation and have stopped responding to standard treatments. Afatinib works by blocking the mutated EGFR signal that tells cancer cells to grow. The goal is to see if the drug can shrink tumors or slow disease progression.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • ECOG-ACRIN Cancer Research Group

    Philadelphia, Pennsylvania, 19103, United States

Conditions

Explore the condition pages connected to this study.