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Sham-Controlled trial to reveal true benefits of heart shock therapy

NCT ID NCT05136131

First seen Jan 07, 2026 · Last updated May 20, 2026 · Updated 19 times

Summary

This study aims to find out if restoring a normal heart rhythm through a procedure called cardioversion truly improves quality of life for people with persistent atrial fibrillation (AF). One hundred adults with AF will be randomly assigned to receive either real cardioversion or a sham (fake) procedure, and neither they nor their doctors will know which they received. By comparing how both groups feel weeks later, researchers hope to clarify whether the procedure itself—not just the expectation of improvement—makes a meaningful difference in daily symptoms like fatigue and shortness of breath.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Southlake Health

    RECRUITING

    Newmarket, Ontario, L3Y 2P9, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Ottawa Heart Institute

    RECRUITING

    Ottawa, Ontario, K1Y 4W7, Canada

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.