Exercise showdown: interval vs. continuous training for stubborn high blood pressure
NCT ID NCT05563077
First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study compares two types of aerobic exercise—interval training and continuous training—over 4 months in 72 adults with resistant hypertension. The goal is to see which type better lowers 24-hour blood pressure and improves related health markers. Participants are randomly assigned to one of the exercise groups or a usual-care control group.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- aerobic exercise training (moderate-intensity interval training or moderate-intensity continuous training)
- What this could lead to
- If it works, this could point toward an effective exercise program to help control blood pressure in people with resistant hypertension.
- What could go wrong
- This is a small, early-stage trial with only 72 participants, so results may not apply to everyone. Exercise may not lower blood pressure enough to replace medication.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 72 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2022
- Expected to finish
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Nov 2025
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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30 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with resistant hypertension (RH) (i.e., systolic BP/diastolic BP \>130/80 mmHg according to the American College of Cardiology/American Heart Association) despite the concurrent use of three or more antihypertensive drugs - commonly including a diuretic, a long-acting calcium channel blocker, and a blocker of the renin-angiotensin system. RH also includes patients whose BP achieves target values on ≥ 4 antihypertensive. medications (i.e., 'controlled' RH). * Adherence to prescribed medications. * Willing to be randomized to one of the 3 groups. * Informed consent. Exclusion Criteria: * Exclusion criteria will include exercising more than 30 minutes on 3 days or more weekly. * Severe ischemic heart disease, major psychiatric disorder and other health contraindications that may interfere in the evaluations or interventions.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Universidad Europea Madrid (UEM)
Madrid, Madrid, 28670, Spain
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