Which exercise boosts heart efficiency best? new trial aims to find out
NCT ID NCT07485400
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study will compare two types of aerobic exercise—interval training and continuous training—in 48 people with stable coronary artery disease. Participants will exercise twice a week for 8 weeks as part of a cardiac rehab program. Researchers will measure heart efficiency, exercise tolerance, blood pressure, and quality of life to see which approach works better.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- aerobic exercise training (interval or continuous)
- What this could lead to
- If successful, this could show that one type of aerobic exercise is better for improving heart efficiency and daily function in people with heart disease.
- What could go wrong
- This is a small, early-stage trial with only 48 participants, so results may not apply to everyone. The study is not yet recruiting, and the intervention is exercise, not a drug, so benefits may be modest.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 48 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
Mar 2026
An estimate. Start dates often move.
- Expected to finish
-
Jul 2026
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
40 to 75 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Confirmed diagnosis of cardiovascular disease requiring cardiac rehabilitation, with medical indication for a supervised exercise training program. * Prognostic risk classified as low or moderate according to the clinical risk stratification established in the unit, considering: * Killip class I or II (absence or mild heart failure)¹. * Absence of recent acute myocardial infarction (\< 1 month) or presence of a stable previous infarction. * Stable and well-controlled cardiovascular symptoms. * Physical capacity demonstrated in functional tests ≥ 5 METs, preferably \> 7 METs for low-risk patients. * Age between 40 and 75 years. * Ability to perform physical exercise without absolute contraindications. * Written informed consent and willingness to attend the scheduled sessions twice per week for 8 weeks. Exclusion Criteria: * High prognostic risk, defined by: * Killip class \> III (moderate to severe heart failure). * Recent acute myocardial infarction (\< 1 month) with clinical instability. * Active anginal symptoms or decompensated heart failure. * Physical capacity \< 5 METs on functional testing, indicating severely reduced exercise capacity. * Presence of complex or unstable arrhythmias contraindicating vigorous physical exercise. * Concomitant diseases that may limit participation or compromise safety (e.g., advanced pulmonary disease, severe renal failure, severe neuromuscular disorders). * Absolute medical contraindications to maximal strength or interval training (e.g., aortic aneurysm, uncontrolled hypertension). * Participation in another clinical trial or concurrent rehabilitation program. * Inability to comply with attendance requirements or to follow the intervention protocol.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Ischemic heart disease are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- 10,000 nurses tracked to uncover chronic disease triggers
- Can a new electric pulse technique tame Post-Heart-Attack heart rhythms faster?
- A 7,000-Person trial asks: is lifelong aspirin necessary for older hearts?
- CT-Guided heart exams could cut radiation and time
- Can a higher dose of adenosine sharpen heart scans?
- Dental repair may boost heart and metabolic health