Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Exercise may reverse chemo heart damage in childhood cancer survivors

NCT ID NCT04036032

Disease control Sponsor: Connecticut Children's Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether a 3-month aerobic exercise program could improve heart function in 47 childhood cancer survivors who had been treated with anthracycline chemotherapy. Participants chose their own exercise and received support at a YMCA. The goal was to see if exercise could reverse some of the heart damage caused by the chemotherapy.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
aerobic exercise program
What this could lead to
If it works, this could point toward a simple, non-drug way to help protect the hearts of childhood cancer survivors who received certain chemotherapy.
What could go wrong
This is a small, completed study with only 47 participants, so results may not apply to everyone. Exercise may not reverse heart damage for all survivors.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

47 people

The number who actually took part.

Started

Jun 2015

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients who are over 9 years of age and who have had anthracycline chemotherapy treatments that were completed over 2 years ago will be asked to participant in the study. Patients from the oncology clinic and the Stars clinic will be asked to participate.

Ages

9 to 99 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Long-term childhood cancer survivors greater than 9 years of age\* * Exposed to anthracycline chemotherapy \* Age \> 9 years of age was chosen to avoid the need for general anesthesia or sedation Exclusion Criteria: * Contraindications to CMRI\* * Individuals needing sedation to complete the cMRI * Subject not able to perform stress test. * Pregnancy\*\* * Non-English speaking individuals * Orbital X-Ray confirmed to have metal in the eye or patient confirmed to have metal in the eye

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Cancer are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

cancer Cardiotoxicity childhood malignant neoplasm neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cancer Cardiotoxicity

Contacts and locations

Locations

  • CT Children's Medical Center

    Hartford, Connecticut, 06106, United States

  • Nationwide Children's Hospital

    Columbus, Ohio, 43205, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.