Can exercise dose improve heart health? study tests the best amount
NCT ID NCT02514564
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how different amounts of aerobic exercise affect blood flow and fitness in 115 people with heart disease. Participants joined a cardiac rehab program and were monitored for changes in skin blood flow and oxygen use during exercise. The goal is to find the most effective exercise volume for improving cardiovascular health.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- aerobic exercise training
- What this could lead to
- If successful, this could help doctors prescribe the right amount of exercise to improve heart health and fitness in people with cardiovascular disease.
- What could go wrong
- This is a completed study, but the results may not apply to all heart patients. Exercise benefits are well-known, so the main question is about the optimal dose, not a breakthrough.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
115 people
The number who actually took part.
- Start date
-
Dec 2014
- Finished
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Dec 2016
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients treated in the hospital in which the exercise will be performed.
- Ages
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40 to 80 years
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * sedentarism for at least 6 months; * clinical diagnosis for coronary artery disease (occurrence of any acute coronary syndrome, including ST elevation or non-ST elevation myocardial infarction or unstable angina or by the diagnosis of obstructive coronary artery disease on coronary angiography in patients with stable angina). Exclusion Criteria: * nephropathies; * decompensated cardiovascular diseases; * liver diseases.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Instituto Nacional de Cardiologia
Rio de Janeiro, Rio de Janeiro, 21040-900, Brazil
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