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Exercise after brain injury: small study hints at cognitive benefits

NCT ID NCT07429526

Knowledge-focused Sponsor: Danderyd Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This small pilot study looked at whether aerobic exercise can improve memory, attention, and fatigue in people who had a stroke or traumatic brain injury. Twelve participants were split into two groups: one did 30 minutes of aerobic exercise 3-4 times a week for 8 weeks, while the other continued their usual routine. The study used memory and attention tests, as well as brain scans, to measure any changes. The goal was to gather initial data to guide future, larger studies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

12 people

The number who actually took part.

Started

Nov 2013

Finished

Jun 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * \- First stroke/TBI with CT/MRI verified injury, (moderate to severe brain injury) * Age 18-65 years * at least 3 months after injury * Fluent in Swedish Selection criteria * Cognition: * one standard deviation (SD) below age adjusted normal in at least one of the following tests: verbal memory, visual memory, working memory or attention * be able to follow instructions during neuropsychological (NP) testing. * be able to reach 60-80% of estimated maximal heart rate (HRmax= 220-age) during aerobic testing and training Exclusion Criteria: * \- Severe heart disease * Cognitive defects, not due to the actual stroke or TBI * Moderate depression/anxiety, defined as \>10 respectively on HADS * Severe aphasia * Not fulfilling criterias for MRI (such as pregnancy, having metal parts implanted in the body, afraid of cramped spaces)

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Conditions

The condition(s) this trial relates to.

Fatigue stroke disorder traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Stroke TBI

Contacts and locations

Locations

  • Danderyds Sjukhus, Rehabiliteringsmedicinska Universitets Kliniken Stockholm

    Stockholm, 14186, Sweden

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