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New ultrasound tech aims to sharpen breast cancer detection

NCT ID NCT07206888

Diagnosis Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests advanced ultrasound signal processing to make breast images clearer. Researchers will compare new beamforming methods to standard ultrasound in 252 women with breast findings like cysts or microcalcifications. The goal is to better see important features and tell solid from fluid-filled masses, and benign from malignant ones.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Ultrasound imaging with advanced beamforming (and optionally photoacoustic imaging)
What this could lead to
If successful, this could lead to clearer breast ultrasound images, helping doctors spot microcalcifications and distinguish benign from malignant masses more accurately.
What could go wrong
This is an early-phase imaging study, not a treatment trial. The new methods may not significantly improve detection or could be less reliable than current techniques.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 252 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2017

Expected to finish

Jan 2037

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Johns Hopkins Hospital

Ages

18 years and older

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Female adults (age \>18 years) with at least one of the following: * Macrocalcification(s) detected in x-ray 2D or 3D mammography images * Macrocalcification(s) located next to cyst (or other identifiable landmark on an ultrasound image) * A cyst, mass, or finding detected in diagnostic/screening ultrasound or mammography Exclusion Criteria: (when performing ultrasound imaging only) * Children (age \< 18 years) are excluded (when performing ultrasound imaging with light, i.e., optoacoustic imaging) * Children (age \< 18 years) are excluded * Is pregnant * Has open sores including insect bites, rash, poison ivy, and chafing on the skin of the ipsilateral breast * Is experiencing phototoxicity associated with currently taking, or having taken, photosensitizing agents within the previous 72 hours such as sulfonamides, ampicillin, tetracycline * Is currently undergoing phototherapy * Has a history of any photosensitive disease (e.g., porphyria, lupus erythematosus) or is undergoing treatment for a photosensitive disease and is experiencing photosensitivity

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Conditions

The condition(s) this trial relates to.

Arachnodactyly breast cancer breast cyst breast neoplasm calcinosis Cysts

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Breast cancer Breast cyst Microcalcification

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Johns Hopkins Outpatient Center

    Baltimore, Maryland, 21209, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.