Can a Mid-Treatment scan make radiation smarter?
NCT ID NCT03403465
First seen Nov 21, 2025 · Last updated Jun 23, 2026 · Updated 29 times
Summary
This study is testing whether doing a special PET scan during radiation treatment can help doctors adjust the plan to better target tumors and spare healthy tissue. It involves 90 adults with cervical, vulvar, esophageal, or anal cancer. The goal is to see if this approach improves outcomes like tumor control and survival.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Duke University Medical Center
Durham, North Carolina, 27710, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
FDG PET scan (imaging test)
What this could lead to
If successful, this could show that a mid-treatment PET scan helps doctors personalize radiation therapy, potentially improving tumor control and reducing damage to healthy tissue.
What could go wrong
This is a small, early-phase study focused on gathering information, not proving a new treatment works. The PET scan may not lead to better outcomes for all patients.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.