Could fewer immunotherapy doses be enough for some melanoma patients?
NCT ID NCT03122522
First seen May 12, 2026 · Last updated May 23, 2026 · Updated 3 times
Summary
This study is for people with advanced melanoma that cannot be removed by surgery. It tests a flexible approach to giving two immunotherapy drugs (ipilimumab and nivolumab). Instead of always giving four doses, doctors will check after two doses. If the tumor is shrinking, no more doses may be needed. If not, patients can get more doses, even beyond the usual four. The goal is to see if this personalized dosing works as well or better than the standard schedule.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Brigham and Women's Hospital (Data and Specimen Analysis Only)
Boston, Massachusetts, 02115, United States
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Columbia University (Data Analysis Only)
New York, New York, 10032, United States
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Hartford Healthcare Alliance (Data Collection Only)
Hartford, Connecticut, 06102, United States
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Hospital for Special Surgery (Data Analysis)
New York, New York, 10021, United States
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JOHNS HOPKINS HOSPITAL (Data Analysis Only)
Baltimore, Maryland, 21287, United States
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Jaykumar Thumar
Hartford, Connecticut, 06102, United States
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Lehigh Valley Health Network (Data Collection Only)
Allentown, Pennsylvania, 18103, United States
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Memorial Sloan Kettering Basking Ridge
Basking Ridge, New Jersey, 07920, United States
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Memorial Sloan Kettering Bergen
Montvale, New Jersey, 07645, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Memorial Sloan Kettering Commack
Commack, New York, 11725, United States
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Memorial Sloan Kettering Monmouth
Middletown, New Jersey, 07748, United States
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Memorial Sloan Kettering Nassau
Uniondale, New York, 11553, United States
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Memorial Sloan Kettering Westchester
Harrison, New York, 10604, United States
Conditions
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