Could fewer immunotherapy doses be enough for some melanoma patients?

NCT ID NCT03122522

First seen May 12, 2026 · Last updated May 15, 2026 · Updated 1 time

Summary

This study looks at whether giving only 2 doses of the immunotherapy combination (ipilimumab + nivolumab) is enough for patients with advanced melanoma who show early benefit. If not, they can receive more doses, even beyond the usual 4. The goal is to personalize treatment and reduce unnecessary side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Brigham and Women's Hospital (Data and Specimen Analysis Only)

    Boston, Massachusetts, 02115, United States

  • Columbia University (Data Analysis Only)

    New York, New York, 10032, United States

  • Hartford Healthcare Alliance (Data Collection Only)

    Hartford, Connecticut, 06102, United States

  • Hospital for Special Surgery (Data Analysis)

    New York, New York, 10021, United States

  • JOHNS HOPKINS HOSPITAL (Data Analysis Only)

    Baltimore, Maryland, 21287, United States

  • Jaykumar Thumar

    Hartford, Connecticut, 06102, United States

  • Lehigh Valley Health Network (Data Collection Only)

    Allentown, Pennsylvania, 18103, United States

  • Memorial Sloan Kettering Basking Ridge

    Basking Ridge, New Jersey, 07920, United States

  • Memorial Sloan Kettering Bergen

    Montvale, New Jersey, 07645, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Commack

    Commack, New York, 11725, United States

  • Memorial Sloan Kettering Monmouth

    Middletown, New Jersey, 07748, United States

  • Memorial Sloan Kettering Nassau

    Uniondale, New York, 11553, United States

  • Memorial Sloan Kettering Westchester

    Harrison, New York, 10604, United States

Conditions

Explore the condition pages connected to this study.