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AI-Powered texts aim to help smokers beat the habit

NCT ID NCT04720625

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 31, 2026 · Last updated Jul 31, 2026

Summary

This trial tests a computer program called Adapt2Quit that sends personalized motivational text messages to help smokers quit. The messages are chosen based on how each participant rates them, aiming to be more effective than standard quitline texts. The study involves socioeconomically disadvantaged smokers who are current smokers and have a texting-enabled phone. The main goal is to see if these tailored messages lead to more people quitting smoking, verified by breath tests at six months.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Adapt2Quit, a machine-learning system that sends personalized motivational text messages to help smokers quit
What this could lead to
If effective, this approach could offer a low-cost, scalable way to help socioeconomically disadvantaged smokers quit, reducing smoking-related health disparities.
What could go wrong
The trial is testing a behavioral intervention, and results may vary. Success depends on engagement and may not generalize to all smokers.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

757 people

The number who actually took part.

Started

Jun 2021

Finished

Mar 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 99 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Current smoker * Socioeconomically disadvantaged (SED) (using the following criteria: unemployed or underemployed, low income as defined by the federal poverty level guidelines, uninsured or underinsured, and/or have less than a high school education) * English-speaking * Active in care (at least two clinical visits in the last year) * Have a texting-enabled cell phone Exclusion Criteria: * Not a current smoker * Adults unable to consent * Individuals who are not yet adults (infants, children, teenagers) * Prisoners * Pregnant women * Pilot study participants

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Conditions

The condition(s) this trial relates to.

Tobacco Smoking

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Baystate Health

    Springfield, Massachusetts, 01199, United States

  • Johns Hopkins University

    Baltimore, Maryland, 21287, United States

  • University of Massachusetts Medical School

    Worcester, Massachusetts, 01655, United States

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