AI-Powered texts aim to help smokers beat the habit
NCT ID NCT04720625
First seen Jul 31, 2026 · Last updated Jul 31, 2026
Summary
This trial tests a computer program called Adapt2Quit that sends personalized motivational text messages to help smokers quit. The messages are chosen based on how each participant rates them, aiming to be more effective than standard quitline texts. The study involves socioeconomically disadvantaged smokers who are current smokers and have a texting-enabled phone. The main goal is to see if these tailored messages lead to more people quitting smoking, verified by breath tests at six months.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Adapt2Quit, a machine-learning system that sends personalized motivational text messages to help smokers quit
- What this could lead to
- If effective, this approach could offer a low-cost, scalable way to help socioeconomically disadvantaged smokers quit, reducing smoking-related health disparities.
- What could go wrong
- The trial is testing a behavioral intervention, and results may vary. Success depends on engagement and may not generalize to all smokers.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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757 people
The number who actually took part.
- Started
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Jun 2021
- Finished
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Mar 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 99 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Current smoker * Socioeconomically disadvantaged (SED) (using the following criteria: unemployed or underemployed, low income as defined by the federal poverty level guidelines, uninsured or underinsured, and/or have less than a high school education) * English-speaking * Active in care (at least two clinical visits in the last year) * Have a texting-enabled cell phone Exclusion Criteria: * Not a current smoker * Adults unable to consent * Individuals who are not yet adults (infants, children, teenagers) * Prisoners * Pregnant women * Pilot study participants
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Baystate Health
Springfield, Massachusetts, 01199, United States
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Johns Hopkins University
Baltimore, Maryland, 21287, United States
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University of Massachusetts Medical School
Worcester, Massachusetts, 01655, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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