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Real-World check: does apalutamide deliver outside clinical trials?

NCT ID NCT06019676

First seen Nov 01, 2025 · Last updated May 19, 2026 · Updated 27 times

Summary

This study follows 170 men with metastatic hormone-sensitive prostate cancer who choose to take apalutamide as part of their normal treatment. Researchers will track PSA levels and use questionnaires to measure fatigue, thinking skills, and quality of life over two years. The goal is to see how well the drug works in real-world settings, beyond the strict conditions of earlier trials.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust

    Cambridge, CB2 0QQ, United Kingdom

  • Buckinghamshire Healthcare NHS Trust

    Aylesbury, HP21 8AL, United Kingdom

  • Clatterbrdige Cancer Centre, NHS Foundation Trust

    Liverpool, CH63 4JY, United Kingdom

  • East Lancashire Hospitals NHS Trust

    Blackburn, BB2 3HH, United Kingdom

  • Freeman Hospital, The Newcastle upon Tyne Hospitals NHS Foundation Trust

    Newcastle, NE7 7DN, United Kingdom

  • Northern Ireland Cancer Centre, Belfast Health & Social Care Trust

    Belfast, BT9 7AB, United Kingdom

  • South Tyneside and Sunderland NHS Foundation Trust

    Newcastle, NE34 0PL, United Kingdom

  • The James Cook University Hospital, South Tees Hospitals NHS Foundation Trust

    Middlesbrough, TS4 3BW, United Kingdom

  • The Royal Marsden Hospital

    Sutton, Surrey, SM2 5PT, United Kingdom

  • The University Hospital of North Tees

    Stockton-on-Tees, TS19 8PE, United Kingdom

  • University Hospitals of Morecambe Bay NHS Foundation Trust

    Lancaster, LA1 4RP, United Kingdom

  • Velindre Cancer Centre, Velindre University NHS Trust

    Cardiff, CF14 2TL, United Kingdom

Conditions

Explore the condition pages connected to this study.