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Stomach bleeding linked to kidney damage: new study to track who is at risk

NCT ID NCT07636083

Knowledge-focused Sponsor: Sohag University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will follow 200 adults hospitalized with upper gastrointestinal bleeding to see how many develop acute kidney injury. Researchers will also look for factors that make kidney damage more likely, such as the cause of bleeding. No new treatments are being tested—patients receive standard care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors identify which patients with upper GI bleeding are at highest risk for kidney injury, allowing earlier monitoring and prevention.
What could go wrong
This is an observational study, not a treatment trial, so it won't test any new therapy. Results may not apply to hospitals outside of Egypt or to patients with different health profiles.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 200 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

May 2026

An estimate. Start dates often move.

Expected to finish

May 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients presenting with acute upper gastrointestinal bleeding and admitted to Sohag University Hospitals, including both ward and ICU patients, who meet the eligibility criteria and have available renal function data.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients aged 18 years or older * Patients presenting with clinical features suggestive of acute upper gastrointestinal bleeding (UGIB), including hematemesis, coffee-ground vomiting, or melena * Diagnosis of UGIB confirmed by upper gastrointestinal endoscopy or strong clinical evidence when endoscopy is not immediately available * Patients admitted to Sohag University Hospitals (medical wards or intensive care unit) * Availability of renal function data, including at least one serum creatinine measurement at admission and serial measurements during hospitalization * Availability of baseline renal function (previous serum creatinine within 3-12 months) or estimable baseline during hospitalization Exclusion Criteria: * Patients with end-stage renal disease (ESRD) on chronic dialysis * Patients with a history of renal transplantation * Patients with advanced chronic kidney disease stage 5 (eGFR \<15 mL/min/1.73 m²) not on dialysis * Patients with lower gastrointestinal bleeding * Patients with incomplete or missing essential renal function data * Patients discharged or deceased within 24 hours of hospital admission * Pregnant patients * Patients with acute kidney injury at presentation due to causes other than UGIB

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Conditions

The condition(s) this trial relates to.

acute kidney injury Gastrointestinal Hemorrhage kidney failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute kidney injury Upper gastrointestinal bleeding

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Sohag University Hospitals

    Sohag, Egypt

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