Acupuncture showdown: manual vs. electric for constipation relief
NCT ID NCT07506122
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares manual acupuncture and electroacupuncture to see which works better for people with long-term constipation. 72 adults will receive 12 weeks of treatment, three times per week. The main goal is to see if bowel movements increase to at least three per week. Researchers will also look at changes in gut bacteria and brain activity to understand how acupuncture might help.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- acupuncture (manual and electroacupuncture)
- What this could lead to
- If successful, this could clarify which type of acupuncture works best for constipation and why, potentially leading to a standard non-drug treatment option.
- What could go wrong
- This is a small, early-stage study with no placebo group, so results may not prove effectiveness. Acupuncture effects can vary widely between individuals.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 72 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2026
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Meet Rome IV diagnostic criteria for functional constipation * Symptoms present for ≥6 months, meeting diagnostic criteria in the last 3 months * Mean weekly complete spontaneous bowel movements (CSBMs) ≤2 during 14-day baseline period * Age 18-75 years * No use of constipation medications for at least 2 weeks prior to treatment (except rescue medication) * No acupuncture treatment for constipation in the past 3 months * Not currently participating in another clinical trial * Willing and able to provide written informed consent Exclusion Criteria: * Constipation secondary to other causes (IBS, organic diseases, medications, endocrine disorders, metabolic disorders, neurological disorders, or gastrointestinal surgery) * Loose or watery stools (Bristol type 6 or 7) \>1 time during baseline without laxative use * History of pelvic floor dysfunction * Use of probiotics, fiber supplements, or laxatives within 2 weeks prior to treatment (2-week washout required) * Severe hemorrhoids or anal fissures * Severe or uncontrolled heart, liver, or kidney disease; abdominal aortic aneurysm; hepatosplenomegaly; cognitive impairment; or psychiatric disorders * Dependence on opioids or anticholinergic drugs * Red flags: unexplained weight loss \>10% in 3 months, hematochezia or positive fecal occult blood, family history of colon cancer (first-degree relative diagnosed \<50 years), anemia (Hb \<110 g/L), or elevated inflammatory markers * Contraindications to acupuncture: coagulation disorders or use of anticoagulants * Pregnancy or breastfeeding * Unable to comply with follow-up or contraindications to MRI (e.g., cardiac pacemaker, non-titanium aneurysm clips, metallic implants, claustrophobia)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
NOT_YET_RECRUITINGWuhan, Hubei, 430030, China
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Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
RECRUITINGWuhan, Hubei, 430030, China
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