Can acupuncture ease breast cancer pain? new trial investigates
NCT ID NCT02754752
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 2 trial tests whether electroacupuncture can reduce chronic pain in women who have completed treatment for stage I-III breast cancer. 111 participants will receive either real acupuncture, sham acupuncture, or no treatment. The goal is to see if this gentle needle therapy can lower pain scores and improve quality of life.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- electroacupuncture
- What this could lead to
- If it works, this could offer a drug-free option for managing long-term pain after breast cancer surgery.
- What could go wrong
- This is a mid-stage trial with only 111 participants, so results may not apply to everyone. The sham acupuncture group also limits how much benefit is truly from the needles.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
-
111 people
The number who actually took part.
- Started
-
Sep 2016
- Expected to finish
-
Dec 2026
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
-
Female participants only
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Be adult women \>/= 18 years of age. * Be able to read, write, and speak English * Able to give informed consent * Have a history of stage I, II, or III breast cancer * Have a documented visit with an oncologist during the previous 12-months * Have no current evidence of disease * Have persistent pain (unrelated to aromatase inhibitors or chemotherapy-induced peripheral neuropathy) for at least 3 months following treatment for breast cancer * Have pain severity (arithmetic mean of four pain severity items) \>= 2 on Brief Pain Inventory (BPI) * Have worst pain \>= to 4 (0-10 numeric rating scale \[NRS\]) in the preceding week * Be willing and able to adhere to all study-related procedures * Have completed all cancer treatment (including surgery, chemotherapy and/or radiation) at least 4 months prior to enrollment * Have documented lab work with absolute neutrophil count (ANC) \>= 1.0 K/uL and platelets \>= 50 K/uL in the past 12 months * If applicable, maintain self-management of lymphedema symptoms being performed at home at time of study entry Exclusion Criteria: * Metastatic breast cancer (stage IV) * Known bleeding disorder per patient reported history * Cardiac pacemaker or other implanted electronic devices * New or planned new lymphedema treatment during the study period * Currently receiving or ever received acupuncture for present pain condition * Received acupuncture with electrical stimulation for any condition * Received acupuncture for any condition in the past year
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
M D Anderson Cancer Center
Houston, Texas, 77030, United States
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Other studies related to the condition(s) this trial covers.
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