Can a simple exercise program help seniors with kidney disease?
NCT ID NCT06089057
First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 3 times
Summary
This pilot study tests a 16-week physical activity and power training program for up to 30 older Veterans with advanced chronic kidney disease. The main goal is to see if the program is doable and well-tolerated. Participants will be pre-frail or have difficulty walking, and the study aims to improve leg strength and self-care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2026
- Expected to finish
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Sep 2029
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a US federal agency other than the NIH.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Participant's nephrologist and/or primary care physician agree that participant may enroll in trial * Participants classified as pre-frail per Fried Frailty phenotype due to slowness (time taken to walk 15 feet is greater than 6 seconds) in Aim 1, OR who report 'YES' to any of the following: * "For health or physical reasons, do you have difficulty in walking a mile (5-6 blocks)?", OR * "If no, have you changed the way you walk half a mile (5-6 blocks) because of underlying health problems?", OR * "For health or physical reasons, do you have difficulty in climbing 1 flight of stairs (10 steps)?", OR * "If no, have you changed the way you climb 1 flight of stairs (10 steps) because of health problems?" Exclusion Criteria: * Myocardial infarction or unstable angina within the prior six months based on electronic medical record review or self-report * Uncontrolled cardiac arrythmia within the prior six months based on electronic medical record review or self-report * Systolic blood pressure \> 180 mm Hg and/or diastolic blood pressure \> 110 mm Hg on more than one occasion within prior six months based on electronic medical record review or self-report * Cerebrovascular event and/or transient ischemic attack within prior six months based on electronic medical record review or self-report * Abnormal cardiac stress test within the past year based on electronic medical record review or self-report * Hemoglobin of 10 g/dL or less based on electronic medical record review or self-report * Class IV heart failure based on electronic medical record review or self-report * Dyspnea and/or chest pain at rest * Dependence on wheelchair for mobility * Permanent residence in nursing home or other long-term care facility * Terminal illness or other hospice-qualifying medical condition * Planned move away from middle Tennessee within the next year * Planned major surgery in the next six months * Blindness * Concurrent enrollment in physical therapy or structured exercise program * Anticipated dialysis or kidney transplant in upcoming three months * Non-English speaking * Severe cognitive impairment based on electronic medical record review or self-report
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Tennessee Valley Healthcare System Nashville Campus, Nashville, TN
Nashville, Tennessee, 37212-2637, United States
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Other studies related to the condition(s) this trial covers.
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