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Can talk therapy ease the mental burden of HIV? new study tests two approaches

NCT ID NCT07652918

Symptom relief Sponsor: Sadia Batool Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two types of talk therapy—Acceptance and Commitment Therapy (ACT) and Cognitive Behavioral Therapy (CBT)—for HIV/AIDS patients experiencing psychological distress. 72 adults on antiretroviral therapy will receive 8 weekly sessions of either therapy or standard care. Researchers will measure changes in depression, anxiety, stress, stigma, wellbeing, social support, and medication adherence.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Acceptance and Commitment Therapy (ACT) and Cognitive Behavioral Therapy (CBT)
What this could lead to
If successful, this could show that brief talk therapies help HIV/AIDS patients manage distress, stigma, and improve wellbeing and medication adherence.
What could go wrong
This is a small, early-stage trial with only 72 participants, so results may not apply broadly. The therapies are brief and may not produce lasting change.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 72 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2025

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participants must have a documented medical diagnosis of HIV/AIDS by a healthcare professional. * Participants should fall within a specified age range, typically from 18 years to 40 years older. * ACT and CBT treatments will be made available to participants who are receiving ART. * Participants must be actively receiving or seeking treatment and care for their HIV/AIDS condition at Sheikh Zayed Hospital. * Individuals must express their voluntary willingness to participate in the study and provide informed consent. Exclusion Criteria: * Individuals with severe cognitive impairments that would hinder their ability to engage in assessments or therapy sessions will be excluded. * Individuals with severe psychiatric conditions that require immediate specialized care beyond the scope of the study will be excluded. * Individuals with a history of prior participation in a similar cognitive behavior therapy intervention for HIV/AIDS will be excluded to avoid potential confounding effects from previous treatment experiences

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Conditions

The condition(s) this trial relates to.

AIDS HIV infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV (human immunodeficiency virus) Psychological distress

Contacts and locations

Locations

  • Sheikh Zayed Hospital Rahim Yar Khan

    Rahim Yar Khan, Punjab Province, 64200, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.