Can talking therapy ease the emotional toll of incurable cancer?
NCT ID NCT07124546
First seen Aug 04, 2026 · Last updated Aug 05, 2026 · Updated 1 time
Summary
This trial tests whether Acceptance and Commitment Therapy (ACT), delivered through telehealth group sessions, can help reduce cancer-related distress in patients with incurable hepatobiliary or breast cancer. Participants will learn to cope with difficult thoughts and emotions while focusing on what matters most in life. The study aims to see if this approach is satisfying and feasible for patients, potentially offering a new way to improve quality of life.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Acceptance and Commitment Therapy (ACT) delivered via telehealth group sessions
- What this could lead to
- If effective, this therapy could offer a practical way to reduce emotional distress and improve quality of life for people facing incurable cancers.
- What could go wrong
- This is an early-stage study with a small number of participants, so results may not apply broadly. The therapy may not reduce distress for everyone, and participation requires internet access and English proficiency.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2025
- Expected to finish
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May 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Incurable HBC and breast cancer diagnosis * Age \>= 18 years * Able to provide written informed consent * Verbally endorse cancer distress * Access to the internet * Read and write in English * Reside in the states of Minnesota Exclusion Criteria: * Other psychological therapy that started =\< 2 months prior to prospective enrollment * Inability to actively participate in and learn from group therapy (e.g., active/uncontrolled psychotic symptoms, neurological condition, personality pathology) as determined by clinical judgement in Behavioral Medicine Program (BMP) consultation. Individual therapy or alternative group therapy will be offered to patients ineligible per this criterion * Cancer remission
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Mayo Clinic in Rochester
RECRUITINGRochester, Minnesota, 55905, United States
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