Heart drug switch: can a new pill boost key protein levels?
NCT ID NCT07298044
First seen Jan 11, 2026 · Last updated May 25, 2026 · Updated 22 times
Summary
This study tests a drug called acoramidis in 50 adults with a heart condition called ATTR-CM, where a protein builds up and weakens the heart. Participants have already been taking a similar drug (tafamidis) and will switch to acoramidis for 6 months. The main goal is to see if acoramidis raises blood levels of the protein TTR more than tafamidis did, which may help slow the disease.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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AZ St-Jan Brugge-Oostende A.V.
NOT_YET_RECRUITINGBruges, 8000, Belgium
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Hôpital Erasme/Erasmus Ziekenhuis
NOT_YET_RECRUITINGBrussels, 1070, Belgium
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KVZ Kardiovaskulaeres Zentrum Darmstadt GmbH
NOT_YET_RECRUITINGDarmstadt, Hesse, 64287, Germany
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Klinik Favoriten - 5.Medizinische Abteilung-Kardiologie
NOT_YET_RECRUITINGVienna, State of Vienna, 1100, Austria
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Klinik Ottakring - 3. Medizinische Abteilung mit Kardiologie, internistischer Intensivmedizin und Ambulanz
NOT_YET_RECRUITINGVienna, State of Vienna, 3500, Austria
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Krankenhaus St. Josef Braunau | Innere Medizin I
NOT_YET_RECRUITINGBraunau am Inn, Upper Austria, 5280, Austria
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Medizinische Universität Graz- Klinische Abteilung für Kardiologie
RECRUITINGVienna, Styria, 1030, Austria
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Medizinische Universität Wien- Universitätsklinik für Innere Medizin II, Klinische Abteilung für Kardiologie
NOT_YET_RECRUITINGVienna, State of Vienna, 1090, Austria
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Oslo Universitetssykehus HF, Rikshospitalet
NOT_YET_RECRUITINGOslo, 0424, Norway
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Universitätsklinikum St. Pölten - Lilienfeld - Klinische Abteilung für Innere Medizin 3
WITHDRAWNSankt Pölten, Lower Austria, 1210, Austria
Conditions
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