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Knee surgery showdown: stitch the stump or snip it?

NCT ID NCT07236593

Knowledge-focused Sponsor: Cairo University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compared two ways to repair a torn anterior cruciate ligament (ACL): one where surgeons stitch the torn ligament stump around the new graft, and the standard method where the stump is removed. 190 patients with recent ACL tears were randomly assigned to one of the two procedures. The goal was to see if preserving the stump reduces widening of the bone tunnel, a common complication that can loosen the graft over time.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
surgical procedure (ACL reconstruction with stump suturing or stump resection)
What this could lead to
If stump suturing reduces tunnel widening, it could improve long-term graft stability and reduce the need for revision surgery.
What could go wrong
This is a completed, moderate-sized study, but it only measured tunnel widening on CT scans, not patient function or re-injury rates. The benefit may not translate into better outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

190 people

The number who actually took part.

Started

Jul 2021

Finished

Mar 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 18 and 45 years * Acute ACL injury (\<6 months) * Medically fit for surgery Exclusion Criteria: * Age \<18 or \>45 years * Old or chronic ACL injuries (\>6 months) * Multi-ligamentous knee injuries * Failed previous ACL reconstruction * Associated mal-alignment deformities * Absence of identifiable ACL stump

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Conditions

The condition(s) this trial relates to.

Anterior Cruciate Ligament Injuries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anterior cruciate ligament injury

Contacts and locations

Locations

  • Kasr Alainy

    Cairo, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.