PRP boost for ACL surgery? small study tests knee recovery
NCT ID NCT07269522
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compared knee function after ACL reconstruction using a hamstring graft, with or without adding platelet-rich plasma (PRP). Sixty patients aged 18-40 with ACL injuries were enrolled. The goal was to see if PRP improves outcomes like knee stability and function.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- platelet-rich plasma (PRP)
- What this could lead to
- If PRP improves knee function after ACL surgery, it could become a standard addition to the procedure.
- What could go wrong
- This is a small, completed study (60 patients) without a phase designation. The results may not apply to all patients, and PRP might not provide significant benefit over surgery alone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
60 people
The number who actually took part.
- Started
-
Jan 2022
- Finished
-
Jun 2023
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 40 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Any gender * Aged 18-40 years * With clinically and radiologically confirmed arthroscopic evidence of ACL injury Exclusion Criteria: * With comprised bilateral ACL tears * Lack of fitness due to associated comorbidity * Fractures of lower limb bones and/or spine/neurovascular injuries * Injuries to other knee ligaments * Significant knee joint arthritis * Local skin infections
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Anterior cruciate ligament injury are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Lahore General Hospital
Lahore, Punjab Province, 54000, Pakistan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could a surgical tourniquet skew a key knee stability test?
- Pressure cuff on the leg: a new way to ease pain after ACL surgery?
- Can muscle activity patterns guide ACL recovery?
- Can the ankle fully recover after donating a tendon for ACL repair?
- Mind over knee: can psychological readiness predict a safe return to sport after ACL surgery?
- Extra nerve block may ease pain after ACL repair