Lung cancer screening gets a Heart-Smart upgrade for heavy smokers

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria used for the lung cancer screening implementation study/ TIDL Study: * Women and men * Ages 60 to 79 years old (inclusive) * A smoking history of at least 35 pack-years and 1) being a current smoker or a former smoker who quit less than 10 years prior or 2) having a PLCOm2012 model 6-year risk for lung cancer incidence over 2.6%. * Willingness and ability to comply with scheduled visits, laboratory tests, and other trial procedures * Written informed consent obtained prior to performing any protocol-related procedures * The participant should be affiliated to a social security system Exclusion Criteria used for the lung cancer screening implementation study/ TIDL Study: * Recent abnormal pulmonary findings under work-up of standard care * Having had chest CT \<1 year before potential entry into the study * Current or prior history of lung cancer, renal cancer, melanoma or breast cancer * Inability to provide signed informed consent * Insufficient understanding of the languages in which trial information is available * Psychiatric or other disorders that are incompatible with compliance to the protocol requirements and follow-up * Unable to be followed-up for at least 5-years * Body weight \>140 Kg because of difficulty of conducting the CT exam Inclusion Criteria used for the ACE 5 Study: * Participants from the TIDL Study with non-contrast, non-cardiac chest CT images available as part of the implementation lung cancer screening study * Signed consent for cardiovascular add on-study and agree to protocol, including follow-up visit 1-year after the baseline examination Exclusion Criteria used for the ACE 5 Study: * Any surgical or medical condition, including short life-expectancy, based on medical records or clinical findings prior to randomization, that will impair the ability of the patient to participate in the study * Patients unwilling or unable to comply with the protocol * History of non-compliance to medical management and patients who are considered potentially unreliable, based on information obtained prior to randomization * History or evidence of alcohol or drug abuse with the last 12 months, based on information obtained prior to randomization, that will influence study participation