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New combo therapy shows promise for rare blood cancer

NCT ID NCT02717624

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 23 times

Summary

This early-phase study tests a new drug combination for people with untreated mantle cell lymphoma, a rare blood cancer. Participants receive acalabrutinib plus either bendamustine and rituximab or venetoclax and rituximab. The main goal is to check safety and side effects, not to cure the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Research Site

    Louisville, Kentucky, 40207, United States

  • Research Site

    Ann Arbor, Michigan, 48109, United States

  • Research Site

    Hackensack, New Jersey, 07601, United States

  • Research Site

    Morristown, New Jersey, 07960, United States

  • Research Site

    Lake Success, New York, 11042, United States

  • Research Site

    Columbus, Ohio, 43210, United States

  • Research Site

    Nashville, Tennessee, 37203, United States

  • Research Site

    Houston, Texas, 77030, United States

  • Research Site

    Seattle, Washington, 98109, United States

  • Research Site

    Seattle, Washington, 98122, United States

  • Research Site

    Bologna, 40138, Italy

  • Research Site

    Krakow, 30-510, Poland

  • Research Site

    Lodz, 93-510, Poland

  • Research Site

    Olsztyn, 10-228, Poland

  • Research Site

    Warsaw, 02-106, Poland

Conditions

Explore the condition pages connected to this study.