New hope for lymphoma patients: drug combo shows promise in early trial

NCT ID NCT02717624

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 22 times

Summary

This early-phase study tests a new drug (acalabrutinib) combined with standard treatments (bendamustine and rituximab, or venetoclax and rituximab) in 72 adults with untreated mantle cell lymphoma. The main goal is to check safety and side effects. Participants must not have had prior lymphoma therapy.

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Contacts and locations

Locations

  • Research Site

    Louisville, Kentucky, 40207, United States

  • Research Site

    Ann Arbor, Michigan, 48109, United States

  • Research Site

    Hackensack, New Jersey, 07601, United States

  • Research Site

    Morristown, New Jersey, 07960, United States

  • Research Site

    Lake Success, New York, 11042, United States

  • Research Site

    Columbus, Ohio, 43210, United States

  • Research Site

    Nashville, Tennessee, 37203, United States

  • Research Site

    Houston, Texas, 77030, United States

  • Research Site

    Seattle, Washington, 98109, United States

  • Research Site

    Seattle, Washington, 98122, United States

  • Research Site

    Bologna, 40138, Italy

  • Research Site

    Krakow, 30-510, Poland

  • Research Site

    Lodz, 93-510, Poland

  • Research Site

    Olsztyn, 10-228, Poland

  • Research Site

    Warsaw, 02-106, Poland

Conditions

Explore the condition pages connected to this study.