New drug cocktail targets hard-to-treat leukemias in early trial
NCT ID NCT03595917
First seen Nov 04, 2025 · Last updated May 24, 2026 · Updated 29 times
Summary
This early-phase study tests a new drug (ABL001) combined with three existing medicines (dasatinib, prednisone, and blinatumomab) for people with BCR-ABL positive B-cell acute lymphoblastic leukemia or chronic myeloid leukemia in lymphoid blast crisis. The main goal is to find the safest dose of ABL001 and see how well the combination works at putting the cancer into remission. About 40 to 65 adults will take part.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Beth Israel Deaconess Medical Center
RECRUITINGBoston, Massachusetts, 02215, United States
Contact
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Dana Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02115, United States
Contact
Contact
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Roswell Park Comprehensive Cancer Center
RECRUITINGBuffalo, New York, 14203, United States
Contact Phone: •••-•••-••••
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University of Chicago Comprehensive Cancer Center
RECRUITINGChicago, Illinois, 60637, United States
Contact Phone: •••-•••-••••
Conditions
Explore the condition pages connected to this study.