New hope for hard-to-treat leukemias? early trial combines four drugs

NCT ID NCT03595917

First seen Nov 04, 2025 · Last updated May 10, 2026 · Updated 27 times

Summary

This early-phase study tests a new drug (ABL001) combined with three other medicines (dasatinib, prednisone, and blinatumomab) for people with B-cell acute lymphoblastic leukemia or chronic myeloid leukemia that has a specific genetic marker (BCR-ABL positive). The main goal is to find the safest dose of ABL001 and see how well the combination works at putting the cancer into remission. About 40 to 65 adults will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beth Israel Deaconess Medical Center

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact

  • Dana Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact

    Contact

  • Roswell Park Comprehensive Cancer Center

    RECRUITING

    Buffalo, New York, 14203, United States

    Contact Phone: •••-•••-••••

  • University of Chicago Comprehensive Cancer Center

    RECRUITING

    Chicago, Illinois, 60637, United States

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.