Stem cells may heal wounds in butterfly children: new trial
NCT ID NCT05464381
First seen Dec 10, 2025 · Last updated May 23, 2026 · Updated 21 times
Summary
This phase 3 trial tests whether a special type of stem cell (ABCB5+ MSCs) given through a vein can safely and effectively heal wounds in people with epidermolysis bullosa, a rare genetic condition that causes fragile, blistering skin. The study includes 91 participants with two forms of the disease (RDEB and JEB), comparing the stem cells to a placebo. The main goal is to see if the treatment leads to complete wound closure.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Andreas Syggros Hospital of Cutaneous Venereal Diseases
Athens, Greece
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Centro Hospitalar e Universitario de Comibra HUC
Coimbra, Portugal
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Department of Dermatology, National Cheng Kung University
Tainan, Taiwan
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EB-Haus Austria; Salzburger Landeskliniken (SALK)
Salzburg, 5020, Austria
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Fundacion Debra Chile
Santiago, Chile
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Great Ormond Street Hospital (GOSH)
London, United Kingdom
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Hospital La Paz
Madrid, Spain
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Hospital Necker-Enfants Malades
Paris, France
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Medical Concierge Centrum Medyczne
Warsaw, Poland
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Ospedale Pediatrico Bambin Gesu
Roma, Italy
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Sanatorio Mater Dei
Buenos Aires, Argentina
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Semmelweis Egyetem
Budapest, Hungary
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Service de Dermatologie Hospital Saint-Louis
Paris, France
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UOSD Pediatria-Alta Intensita di Curà, Ospedale Maggiore
Milan, Italy
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Universitaetsklinik fuer Dermatologie und Allergologie
Nice, France
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Venereal & Skin Diseases Hospital of Thessaloniki
Thessaloniki, Greece
Conditions
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