Butterfly children: stem cell trial offers hope for wound healing

NCT ID NCT05464381

First seen Dec 10, 2025 · Last updated May 13, 2026 · Updated 20 times

Summary

This study tests a stem cell treatment for epidermolysis bullosa, a rare genetic condition causing fragile skin that blisters easily. About 91 participants with severe forms (RDEB or JEB) receive either the stem cells or a placebo through an IV. The main goal is to see if the treatment helps close stubborn wounds completely.

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Contacts and locations

Locations

  • Andreas Syggros Hospital of Cutaneous Venereal Diseases

    Athens, Greece

  • Centro Hospitalar e Universitario de Comibra HUC

    Coimbra, Portugal

  • Department of Dermatology, National Cheng Kung University

    Tainan, Taiwan

  • EB-Haus Austria; Salzburger Landeskliniken (SALK)

    Salzburg, 5020, Austria

  • Fundacion Debra Chile

    Santiago, Chile

  • Great Ormond Street Hospital (GOSH)

    London, United Kingdom

  • Hospital La Paz

    Madrid, Spain

  • Hospital Necker-Enfants Malades

    Paris, France

  • Medical Concierge Centrum Medyczne

    Warsaw, Poland

  • Ospedale Pediatrico Bambin Gesu

    Roma, Italy

  • Sanatorio Mater Dei

    Buenos Aires, Argentina

  • Semmelweis Egyetem

    Budapest, Hungary

  • Service de Dermatologie Hospital Saint-Louis

    Paris, France

  • UOSD Pediatria-Alta Intensita di Curà, Ospedale Maggiore

    Milan, Italy

  • Universitaetsklinik fuer Dermatologie und Allergologie

    Nice, France

  • Venereal & Skin Diseases Hospital of Thessaloniki

    Thessaloniki, Greece

Conditions

Explore the condition pages connected to this study.