Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

New Parkinson's pump shows promise in Real-World test

NCT ID NCT06107426

Disease control Sponsor: AbbVie Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows about 427 adults with advanced Parkinson's disease who are receiving ABBV-951, a continuous infusion under the skin. Researchers want to see how well it controls symptoms like tremors and stiffness over three years in everyday medical practice. Participants attend regular check-ups and fill out questionnaires to track their progress.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
ABBV-951 (foslevodopa/foscarbidopa) given as a continuous infusion under the skin
What this could lead to
If successful, this study could confirm that ABBV-951 effectively reduces 'off' time and improves daily function for people with advanced Parkinson's in routine care.
What could go wrong
This is an observational study, not a controlled trial, so results may be influenced by patient selection or other factors. Long-term benefits and risks are still being assessed.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

427 people

The number who actually took part.

Started

Jan 2024

Expected to finish

May 2029

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Participants with Advanced PD, treated with ABBV-951 according to label and local reimbursement regulations, where applicable.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Eligibility for ABBV-951 therapy in accordance with the approved local label in the participating country and local reimbursement regulations, if applicable. * Diagnosis of levodopa-responsive idiopathic Parkinson's Disease (PD). * Participant must be either: * Cohort A: Naïve to ABBV-951 * Cohort B: Pre-treated with ABBV-951, specifically, participants of Open-Label Extension Studies M15-737 and M20-098 who completed these studies without significant protocol deviations and who did not experience an adverse event (AE) that in the investigator's opinion may indicate an unacceptable safety risk. * Decision to treat with ABBV-951 (or continue the treatment in Cohort B) made by the clinician prior to any decision to approach the participant to participate in this study. * Prior to any study-related procedures being performed, the participant, or legal authorized representative (LAR) has voluntarily signed an Authorization for Use/Disclosure of Data (AUDD)/informed consent form (ICF) according to national regulations after the study has been explained and the participant has had the opportunity to have questions answered. Exclusion Criteria: * Any condition included in the contraindications section of the approved local ABBV-951 label in the participating country. * Mini-Mental State Examination (MMSE) score \< 24. * If the participant has a score of 19-23, he/she can be included if based on the investigator´s judgment the participant is able to handle the therapy and follow the study procedures with the help of a permanent caregiver. * Participation in a concurrent interventional clinical trial from enrollment and throughout the study. * History of significant skin conditions or disorders per investigator´s judgment. In case of temporary affections like recent sunburn, acne, scar tissue, tattoo, open wound, branding, or colorations, the participant should not be included if the investigator considers these as interfering with the infusion of study drug or with study assessments.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Parkinson's disease (PD) are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Parkinson's disease (PD)

Contacts and locations

Locations

  • Atrium Health Wake Forest Baptist Medical Center /ID# 259387

    Winston-Salem, North Carolina, 27157, United States

  • Banner Sun Health Research Institute /ID# 253461

    Sun City, Arizona, 85351, United States

  • Bispebjerg Hospital /ID# 252032

    Copenhagen, Capital Region, 2400, Denmark

  • Boston Medical Center Health System /ID# 269765

    Brighton, Massachusetts, 02135, United States

  • CHUM - Centre hospitalier de l'Universite de Montréal /ID# 269689

    Montreal, Quebec, H2X 0A9, Canada

  • Centre de Recherche St-Louis /ID# 262746

    Québec, Quebec, G1W 4R4, Canada

  • Centrum for neurologi /ID# 252118

    Stockholm, Stockholm County, 113 65, Sweden

  • Cleveland Clinic Lou Ruvo Cent /ID# 259390

    Las Vegas, Nevada, 89106-0100, United States

  • Complejo Hospitalario Universitario de Santiago (CHUS) /ID# 261402

    Santiago de Compostela, A Coruna, 15706, Spain

  • David L. Kreitzman, MD, PC /ID# 259397

    Commack, New York, 11725-6021, United States

  • Evergreenhealth Medical Center /ID# 268120

    Kirkland, Washington, 98034, United States

  • Georgetown University Hospital /ID# 259381

    Washington D.C., District of Columbia, 20007, United States

  • Hadassah Medical Center-Hebrew University /ID# 257717

    Jerusalem, 91120, Israel

  • Hospital Clinico San Carlos /ID# 260922

    Madrid, 28040, Spain

  • Hospital General Universitario de Elche /ID# 254438

    Elche, Alicante, 03203, Spain

  • Hospital Universitario Puerta de Hierro - Majadahonda /ID# 260921

    Majadahonda, Madrid, 28222, Spain

  • Hospital Universitario Virgen de las Nieves /ID# 257588

    Granada, 18014, Spain

  • Hospital Universitario Virgen del Rocio /ID# 254437

    Seville, 41013, Spain

  • Inland Northwest Research /ID# 253460

    Spokane, Washington, 99202-1342, United States

  • Kansas City VA Medical Center /ID# 253466

    Kansas City, Missouri, 64128, United States

  • Kepler Universitaetsklinikum GmbH /ID# 262776

    Linz, Upper Austria, 4020, Austria

  • Klinik Ottakring /ID# 262773

    Vienna, State of Vienna, 1160, Austria

  • Kliniken Beelitz GmbH /ID# 252665

    Beelitz-Heilstätten, 14547, Germany

  • Klinikum Ernst von Bergmann /ID# 252375

    Potsdam, Brandenburg, 14467, Germany

  • Klinikum Osnabrueck GmbH /ID# 252275

    Osnabrück, Lower Saxony, 49076, Germany

  • Klinikum der Universitaet Muenchen Grosshadern /ID# 255574

    Munich, Bavaria, 81337, Germany

  • Knappschaftskrankenhaus Bottrop /ID# 252274

    Bottrop, 46242, Germany

  • Krankenhaus Martha-Maria Halle-Doelau /ID# 260372

    Halle, Saxony-Anhalt, 06120, Germany

  • Medizinische Universitaet Graz /ID# 262774

    Graz, Styria, 8010, Austria

  • Medizinische Universitaet Innsbruck /ID# 262775

    Innsbruck, Tyrol, 6020, Austria

  • N1 Research, LLC /ID# 264221

    Orlando, Florida, 32825-3769, United States

  • NeuroCare Center /ID# 259392

    Canton, Ohio, 44718-2531, United States

  • Northwell Health /ID# 253469

    Lake Success, New York, 11042, United States

  • Northwestern Medicine Primary And Specialty Care Lavin Family Pavilion /ID# 266977

    Chicago, Illinois, 60611, United States

  • Novant Health Neurology and Sleep /ID# 259391

    Charlotte, North Carolina, 28207-1100, United States

  • Ochsner Medical Center - Jefferson Highway /ID# 269764

    New Orleans, Louisiana, 70121, United States

  • Odense University Hospital /ID# 252036

    Odense, Region Syddanmark, 5000, Denmark

  • Parkinson's Disease and Movement Disorders Center of Boca Raton /ID# 253465

    Boca Raton, Florida, 33486, United States

  • Parkinson's Research Centers of America - Palo Alto /ID# 264703

    Palo Alto, California, 94301-2011, United States

  • Parkinson-Klinik Ortenau GmbH&Co KG /ID# 252376

    Wolfach, Baden-Wurttemberg, 77709, Germany

  • Rabin Medical Center. /ID# 257716

    Petah Tikva, 4941492, Israel

  • Rambam Health Care Campus- Haifa /ID# 260421

    Haifa, 3525408, Israel

  • Rigshospitalet Glostrup /ID# 252035

    Glostrup Municipality, Capital Region, 2600, Denmark

  • Sahlgrenska Universitetssjukhuset /ID# 252115

    Gothenburg, Västra Götaland County, 413 46, Sweden

  • Shaare Zedek Medical Center /ID# 257715

    Jerusalem, Jerusalem, 91031, Israel

  • Spitalul Clinic Colentina /ID# 252250

    Bucharest, 020121, Romania

  • Spitalul Clinic Judetean de Urgenta Brasov /ID# 253308

    Brasov, 500326, Romania

  • Spitalul Clinic Judetean de Urgenta Constanta /ID# 252251

    Constanța, 900591, Romania

  • Spitalul Clinic Judetean de Urgenta Targu Mures /ID# 252247

    Târgu Mureş, 540136, Romania

  • Spitalul Clinic Judetean de Urgenta Timisoara /Id# 252248

    Timișoara, Timiș County, 300736, Romania

  • Spitalul Clinic Judetean de Urgenta Timisoara /Id# 252249

    Timișoara, Timiș County, 300736, Romania

  • Tel Aviv Sourasky Medical Center /ID# 254824

    Tel Aviv, Tel Aviv, 6423906, Israel

  • Texas Movement Disorder Specialists /ID# 253473

    Georgetown, Texas, 78628-4126, United States

  • The Chaim Sheba Medical Center /ID# 254823

    Ramat Gan, Tel Aviv, 5265601, Israel

  • The Movement Disorder Clinic of Oklahoma /ID# 253463

    Tulsa, Oklahoma, 74136-6378, United States

  • The Ottawa Hospital - General Campus /ID# 263315

    Ottawa, Ontario, K1H 8L6, Canada

  • The Royal Melbourne Hospital /ID# 259671

    Parkville, Victoria, 3050, Australia

  • Univ Texas HSC San Antonio /ID# 259394

    San Antonio, Texas, 78229-3901, United States

  • University of Alabama at Birmingham - Main /ID# 253477

    Birmingham, Alabama, 35233, United States

  • University of Calgary /ID# 262833

    Calgary, Alberta, T2N 4Z6, Canada

  • University of Florida College of Medicine /ID# 259383

    Gainesville, Florida, 32610, United States

  • University of Miami /ID# 259396

    Miami, Florida, 33138, United States

  • University of Minnesota - Minneapolis /ID# 268121

    Minneapolis, Minnesota, 55455-0341, United States

  • University of South Florida- Neuroscience Institute /ID# 253470

    Tampa, Florida, 33613, United States

  • University of Utah /ID# 253471

    Salt Lake City, Utah, 84112-5500, United States

  • Uppsala University Hospital /ID# 252119

    Uppsala, Uppsala County, 75185, Sweden

  • Vanderbilt University Medical Center /ID# 253474

    Nashville, Tennessee, 37232-0011, United States

  • Westmead Hospital /ID# 259670

    Westmead, New South Wales, 2145, Australia

More trials for these conditions

Other studies related to the condition(s) this trial covers.