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New hope for tough lymphoma: first human trial of ABBV 291 launches

NCT ID NCT06667687

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 26 times

Summary

This early-stage study tests an experimental drug called ABBV 291 in adults with Non-Hodgkin's lymphoma that has returned or stopped responding to standard treatments. The main goals are to check safety, find the best dose, and see if the drug can shrink tumors. About 165 participants worldwide will receive the drug through an IV, and researchers will monitor side effects and disease changes closely.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Aichi Cancer Center /ID# 267471

    RECRUITING

    Nagoya, Aichi-ken, 464-8681, Japan

  • Carolina BioOncology Institute /ID# 265259

    COMPLETED

    Huntersville, North Carolina, 28078, United States

  • Hadassah Medical Center-Hebrew University /ID# 261658

    RECRUITING

    Jerusalem, Jerusalem, 91120, Israel

  • National Cancer Center Hospital East /ID# 261775

    RECRUITING

    Kashiwa-shi, Chiba, 277-8577, Japan

  • START Mountain Region /ID# 267592

    COMPLETED

    West Valley City, Utah, 84119-3602, United States

  • Sir Charles Gairdner Hospital /ID# 268579

    RECRUITING

    Nedlands, Western Australia, 6009, Australia

  • St Vincent's Hospital Melbourne /ID# 261664

    RECRUITING

    Fitzroy Melbourne, Victoria, 3065, Australia

  • Tel Aviv Sourasky Medical Center /ID# 261659

    RECRUITING

    Tel Aviv, Tel Aviv, 6423906, Israel

  • Texas Oncology - Central/South Texas /ID# 270946

    RECRUITING

    Austin, Texas, 78705, United States

  • The Cancer Institute Hospital Of JFCR /ID# 267470

    RECRUITING

    Koto-ku, Tokyo, 135-8550, Japan

  • The Christie /ID# 267177

    RECRUITING

    Manchester, M20 4BX, United Kingdom

  • University Hospitals Plymouth NHS Trust /ID# 267174

    RECRUITING

    Plymouth, PL6 5FP, United Kingdom

  • Virginia Cancer Specialists - Fairfax /ID# 265082

    COMPLETED

    Fairfax, Virginia, 22031, United States

  • Willamette Valley Cancer Institute and Research Center /ID# 270945

    RECRUITING

    Eugene, Oregon, 97401, United States

Conditions

Explore the condition pages connected to this study.