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New Gut-Targeted therapy shows promise for easing Autism-Related irritability

NCT ID NCT04895215

Summary

This study tested whether a medication called AB-2004 could safely reduce irritability in people with autism spectrum disorder. 156 participants with significant irritability were randomly assigned to receive either the medication or a placebo for 8 weeks. Researchers measured changes in irritability and overall severity to see if the treatment was effective and well-tolerated.

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Contacts and locations

Locations

  • Baber Research

    Naperville, Illinois, 60563, United States

  • Brain Mind Centre

    Sydney, New South Wales, 2050, Australia

  • CNS Solutions

    Jacksonville, Florida, 32256, United States

  • CNS Solutions

    Orlando, Florida, 32801, United States

  • Children's Health Queensland Hospital

    South Brisbane, Queensland, 4101, Australia

  • Clinical Research of Southern Nevada

    Las Vegas, Nevada, 89128, United States

  • Cortica Marin

    San Rafael, California, 94903, United States

  • Cortica Westlake

    Westlake Village, California, 91361, United States

  • Harmonex Neuroscience Research

    Dothan, Alabama, 36303, United States

  • IMMUNOe Research Centers

    Centennial, Colorado, 80112, United States

  • Monash Kids Research

    Clayton, Victoria, 3186, Australia

  • Murdoch Children's Research Institute

    Parkville, Victoria, 3052, Australia

  • Nathan S. Kline Institute for Psychiatric Research

    Orangeburg, New York, 10962, United States

  • Ohio State University

    Columbus, Ohio, 43210, United States

  • Optimal Clinical Trials

    Grafton, Auckland, 1010, New Zealand

  • Relaro Medical Trials

    Dallas, Texas, 75243, United States

  • Southwestern Autism Research and Resource Center

    Phoenix, Arizona, 85006, United States

  • Spectrum Neuroscience and Treatment Institute

    New York, New York, 10021, United States

  • University of Arizona

    Tucson, Arizona, 85724, United States

  • University of Missouri, Thompson Center for Autism and Neurodevelopmental Disorders

    Columbia, Missouri, 65201, United States

  • University of South Florida

    Tampa, Florida, 33613, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37212, United States

  • Westmead Children's Hospital

    Sydney, New South Wales, 2145, Australia

  • Yale University

    New Haven, Connecticut, 06519, United States

Conditions

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