Blood clot showdown: which filling helps dental implants heal best?
NCT ID NCT07319494
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a newer version of a blood-derived filling (Advanced Platelet-Rich Fibrin) helps bone and gums heal better than the standard version after a tooth is pulled and a dental implant is placed right away. Sixteen healthy adults with a badly decayed back tooth will receive one of the two fillings. Researchers will check bone thickness and implant stability over six months.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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16 people
The number who actually took part.
- Started
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Jun 2025
- Expected to finish
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Feb 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * The selected patients has a badly decayed mandibular posterior teeth which are indicated for extraction due to dental causes (periapical abscess, trauma or caries) not periodontal as diagnosed by periapical x-ray. * Healthy patients who are classified according to the American Society of Anesthesiologists (ASA)(2022) physical status classification as class I. * Patient age ≥ 20 years old. * Surgical site with sufficient for implant placement. * Sufficient interocclusal space for prosthesis. * Good oral hygiene. * Patients have thick biotype. * Patients have socket class I. Exclusion Criteria: * Active periodontal diseases and periapical lesions not chronic infections. * Patients have parafunctional * History of alcohol or drug dependency, psychological factor that might affect the surgical or prosthodontic treatment. * Smoking. * Pregnant patients. * Patients who are not willing to complete the study.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Delta University For Science And Technology
Al Mansurah, 35516, Egypt