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9-Month TB cure trial shows promise for Drug-Resistant patients

NCT ID NCT03057756

Cure Sponsor: Centre de Recherche Médicale de Lambaréné Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a 9-month treatment plan for people with multidrug-resistant tuberculosis (MDR-TB) in Gabon. The goal was to see if this shorter regimen could cure the disease with fewer side effects. 23 patients aged 15 and older took part, and the study tracked how many were cured and any health problems that occurred.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

23 people

The number who actually took part.

Started

Sep 2015

Finished

May 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

study population will consist of all consecutive patients with bacteriologically proven MDR-TB who fulfil the inclusion criteria .

Ages

15 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria: * Aged 15 years and above * Never been treated with second line anti-TB drugs for more than one month, * Give written consent to participate * Agree to be hospitalised for at least four months in specialised healthcare * Willing to adhere to ambulatory directly observed treatment by a healthcare worker; Exclusion criteria: * Pregnant during inclusion process * Presented with altered clinical status condition as judged by the clinician * Knowing of history of hypersensitivity reaction to any of the drugs to be used * Baseline ECG does not show a QT space superior to 500ms * Refusal to participate into study.

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Conditions

The condition(s) this trial relates to.

multidrug-resistant tuberculosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Multi-drug resistant tuberculosis

Contacts and locations

Locations

  • Centre de Recherches Médicales de Lambaréné

    Lambaréné, Please Select, BP 242, Gabon

More trials for these conditions

Other studies related to the condition(s) this trial covers.