New PET tracer could spot hidden cancers
NCT ID NCT07593209
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing a new radioactive imaging agent called 68Ga-DOTA-EphA2 to help see certain proteins on cancer cells during PET/CT scans. The goal is to improve how doctors detect and monitor malignant tumors. About 30 adults with suspected or confirmed cancer will receive the agent and then have a scan to see where it goes in the body.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- 68Ga-DOTA-EphA2 (a radioactive imaging agent)
- What this could lead to
- If successful, this could provide a new way to detect and monitor certain cancers more accurately using PET/CT scans.
- What could go wrong
- This is a small, early-phase study focused on imaging, not treatment. The agent may not work well for all tumor types, and there is a risk of side effects from the radioactive tracer.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2026
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with Malignant Tumor
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18-80 years * Patients with suspected or histologically confirmed malignant tumors At least one measurable lesion identified by conventional imaging (CT, MRI, or ultrasound) * Eastern Cooperative Oncology Group (ECOG) performance status of 0-2 * Ability to understand the study procedures and provide written informed consent * Adequate organ function allowing PET/CT examination Exclusion Criteria: * Pregnant or breastfeeding women * Severe hepatic, renal, cardiovascular, or pulmonary dysfunction considered --unsuitable for PET/CT imaging * Known allergy or hypersensitivity to study-related compounds * Patients unable to tolerate PET/CT examination or remain still during image acquisition * Participation in other investigational drug or radionuclide studies within 4 weeks prior to enrollment * Any medical or psychiatric condition judged by the investigators to interfere with study participation or interpretation of imaging results
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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PET
RECRUITINGShenyang, Liaoning, 110001, China
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