New PET tracer aims to spot scarring in organs without a needle
NCT ID NCT07459205
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study will test a new imaging agent called 68Ga-1A12, which is used in a PET scan to detect fibrosis (scarring) in organs like the lungs. The goal is to see if this scan can diagnose fibrosis earlier and more accurately than current methods, which often require invasive biopsies. The study plans to enroll 50 adults with suspected or confirmed fibrosis-related disease.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- 68Ga-1A12 (a radioactive tracer for PET imaging)
- What this could lead to
- If successful, this could provide a non-invasive way to detect and monitor fibrosis earlier and more accurately than current methods.
- What could go wrong
- This is a small, early-stage study (50 participants) focused on diagnostic accuracy, not treatment. The tracer may not prove reliable enough for widespread use.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Mar 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
patients suspected or confirmed to have fibrosis-related diseases
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * No gender restriction, age ≥18 years (inclusive); * patients suspected or confirmed to have fibrosis-related disease; * patients eligible for 68Ga-1A12 PET scan * Patients who can provide informed consent (signed by the participant, parent or legal representative) and consent forms in accordance with the guidelines of the clinical research ethics committee. Exclusion Criteria: * patients in critical condition requiring emergency care; * Individuals with druand/or alcohol abuse, or those with allergic predisposition; * women of childbearing potential, pregnant and lactating women; * bacterial, viral or fungal infections that require systemic treatment; * The study excluded participants deemed unsuitable by the investigators.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Daping Hospital
Chongqing, Chongqing Municipality, 400010, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can Device-Preserved donor lungs boost transplant success?
- Patients and families build a living database of pulmonary fibrosis
- Breathing exercises put to the test for scarred lungs
- Can mindfulness ease the emotional toll of pulmonary fibrosis?
- Can a radioactive tracer reveal hidden lung scarring?
- Can AI catch lung scarring that doctors might miss?