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New imaging agent could help doctors see which lung tumors are still growing

NCT ID NCT07619599

First seen Jun 05, 2026 · Last updated Jun 23, 2026 · Updated 3 times

Summary

This early-phase trial is testing a new PET imaging agent called 64Cu-DOTA-pembrolizumab in 6 people with stage IV non-small cell lung cancer who are already on pembrolizumab and need radiation for some growing tumors. The goal is to see if the scan can safely tell the difference between tumors that are still growing and those that are stable. If it works, it could help doctors decide which spots need radiation.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • City of Hope Medical Center

    Duarte, California, 91010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

64Cu-DOTA-pembrolizumab (a radioactive imaging agent)

What this could lead to

If successful, this could help doctors better tell which tumors are still growing during treatment, improving decisions about radiation therapy.

What could go wrong

This is a very early, small pilot study with only 6 participants, so results may not apply widely. The imaging agent may not clearly distinguish tumor types or could cause side effects.

Conditions

The condition(s) this trial relates to.

Brain Neoplasms Lung Neoplasms non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.