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New scoring system may spare epilepsy patients from invasive brain surgery

NCT ID NCT06138808

ENROLLING_BY_INVITATION Knowledge-focused Sponsor: Duke University Source: ClinicalTrials.gov ↗

First seen Feb 16, 2026 · Last updated May 01, 2026 · Updated 16 times

Summary

This study is testing a new scoring system called the 5-SENSE score to see if it can accurately predict where seizures start in the brain for people with hard-to-treat epilepsy. The goal is to help doctors decide who truly needs an invasive test called SEEG, which involves placing electrodes directly into the brain. About 400 participants will be enrolled to see how well the score works, potentially sparing some patients from this risky procedure.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • "Carol Davila" University of Medicine and Pharmacy

    Bucharest, Romania

  • Alfred Health

    Melbourne, Australia

  • Christian Doppler University Hospital Paracelsus Medical University Salzburg and Centre for Cognitive Neuroscience Salzburg

    Salzburg, 5020, Austria

  • Dalhousie Universiry and Hospital

    Dalhousie, Nova Scotia, Canada

  • Danish Epilepsy Centre, Aarhus Universitets Hospital

    Aarhus, 8200, Denmark

  • Department of Clinical Neurosciences chez CHUV; Centre Hospitalier Universitaire Vaudois

    Lausanne, Switzerland

  • Departmet of Neurology, Masaryk University Brno

    Brno, Czechia

  • Duke University Health System

    Durham, North Carolina, 27710, United States

  • Epilepsy Centre, University Hospital Freiburg

    Freiburg im Breisgau, Germany

  • Epilepsy Department University Hospitals of Marseille

    Marseille, France

  • Grenoble Institute of Neurosciences, Centre Hospitalier Universitaire Grenoble Alpes

    Grenoble, France

  • Hospital Universitario y Politecnico La Fe

    Valencia, Spain

  • Mater Health

    Brisbane, Australia

  • Monash University

    Melbourne, Victoria, 3800, Australia

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • Presbyterian-Shadyside Hospital

    Pittsburgh, Pennsylvania, 15232, United States

  • University School of Medicine Kyoto

    Kyoto, 606-8303, Japan

  • University of Florida College of Medicine

    Gainesville, Florida, 32610, United States

  • Wester University

    London, Ontario, Canada

Conditions

Explore the condition pages connected to this study.