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Old drug, new hope: could 4-AP save carpal tunnel patients from surgery?

NCT ID NCT06294821

First seen Sep 30, 2025 · Last updated May 21, 2026 · Updated 33 times

Summary

This study tests whether 4-aminopyridine, a drug already approved by the FDA for other uses, can relieve symptoms of carpal tunnel syndrome or delay the need for surgery. About 160 adults with carpal tunnel who would normally have surgery will take the drug twice daily for 6 weeks. Researchers will track symptom changes using standard hand-function questionnaires and nerve tests over 56 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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