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Breathe away high blood pressure? thai study tests 4-7-8 method

NCT ID NCT07018128

Symptom relief Sponsor: Burapha University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study has two parts. First, it looks at genes that might be linked to high blood pressure in Thai people. Second, it tests whether a specific breathing pattern called 4-7-8 (inhale for 4 seconds, hold for 7, exhale for 8) can help lower blood pressure. About 200 adults with hypertension will practice this breathing twice daily for 3 months. The goal is to see if this simple technique can be an effective, non-drug way to manage blood pressure.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
4-7-8 breathing technique
What this could lead to
If it works, this could offer a simple, drug-free way to help manage blood pressure at home.
What could go wrong
This is a small, early study with only 200 participants. The breathing technique may not lower blood pressure significantly, and results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 200 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2024

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 59 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Study 1: 1. Group of individuals with hypertension Inclusion Criteria: * Male or female * Aged between 18-59 years * Of Thai ethnicity * Diagnosed with hypertension, defined as having an SBP of 140 mmHg or higher, or a DBP of 90 mmHg or higher, or having previously been diagnosed with hypertension and currently taking antihypertensive medication * Originally from various regions of Thailand and currently residing in the eastern region Exclusion Criteria: * Has heart disease, such as valvular stenosis or regurgitation, coronary artery disease, or heart failure * Has obesity, defined as having a body mass index (BMI) of 30 kg/m² or higher * Has a fever or is currently experiencing an infectious disease, such as COVID-19, the flu, or other infections 2. Group of individuals with normal blood pressure Inclusion Criteria: * Male or female * Aged between 18-59 years * Of Thai ethnicity * Does not have hypertension, defined as having an SBP below 130 mmHg and a DBP below 85 mmHg, with no prior diagnosis of hypertension and no history of taking antihypertensive medication * Originally from various regions of Thailand and currently residing in the eastern region Exclusion Criteria: * Has heart disease, such as valvular stenosis or regurgitation, coronary artery disease, or heart failure * Has obesity, defined as having a body mass index (BMI) of 30 kg/m² or higher * Has a fever or is currently experiencing an infectious disease, such as COVID-19, the flu, or other infections Study 2: Inclusion Criteria: * Male or female, aged 35-59 years * Diagnosed with hypertension, with blood pressure levels above the normal range, defined as SBP of 130 mmHg or higher, or DBP of 85 mmHg or higher, and currently taking medication * Originally from various regions of Thailand and currently residing in the eastern region * Able to communicate effectively Exclusion Criteria: * Has respiratory diseases, cardiovascular diseases, cerebrovascular disease, kidney disease, cancer, or immune-related conditions such as allergies, autoimmune diseases (e.g., SLE), immunodeficiency, or rheumatoid arthritis * Is obese, defined as having a body mass index (BMI) of 30 kg/m² or higher * Has a fever or is currently infected, such as with COVID-19, the flu, or other infectious diseases * Is currently pregnant, breastfeeding, or has a history of pregnancy within the 6 months prior to participating in the study

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Conditions

The condition(s) this trial relates to.

hypertensive disorder inherited disease susceptibility Mouth Breathing Respiratory Aspiration

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Breathing, mouth Genetic predisposition to disease

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Faculty of Allied Health Sciences, Burapha University

    RECRUITING

    MueangChonburi, Changwat Chon Buri, 20131, Thailand

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