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Could 3D lung models replace contrast dye in cancer surgery?

NCT ID NCT07234604

Diagnosis Sponsor: University Hospital, Strasbourg, France Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study compares 3D models from non-contrast CT scans to standard contrast CT scans for planning minimally invasive lung cancer surgery. Researchers will check if the 3D models accurately show blood vessels, airways, and tumor location during surgery. If they work, patients might avoid the risks of contrast dye.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could allow surgeons to plan lung cancer surgery using 3D models without needing contrast dye, reducing patient risk.
What could go wrong
This is a small, early-stage study with only 50 participants, so results may not apply broadly. The 3D model might still miss details that contrast CT captures.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Dec 2025

An estimate. Start dates often move.

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

* Adult patient ≥ 18 years * with clinical stage IA lung lesions ≤ 2 cm in diameter AND a suspected or proven malignancy. * Chest CT scan available without and then with contrast * Eligible for VATS or RATS segmentectomy based on respiratory explorations

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patient ≥ 18 years * Patient agreeing to participate in the study * Patient with clinical stage IA lung lesions ≤ 2 cm in diameter AND a suspected or proven malignancy. * Chest CT scan available without and then with contrast * Eligible for VATS or RATS segmentectomy based on respiratory explorations Exclusion Criteria: * Patient refusal to participate in the study * Allergic reactions to radiographic contrast agents * History of ipsilateral cardiothoracic surgery * Open segmentectomy (thoracotomy) * Histology different from that of NSCLC * Inability to provide the subject with informed information (difficulty understanding the subject, insufficient command of French, etc.) * Pregnant or breastfeeding women * Severe cognitive impairment and/or suspicion of lack of compliance or adherence, in the investigator's judgment

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Conditions

The condition(s) this trial relates to.

lung cancer lung neoplasm non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Lung cancer Non-small cell lung cancer

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Service Chirurgie Thoracique - CHU de Strasbourg - France

    Strasbourg, Strasbourg, 67091, France

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