Experimental CAR t therapy targets Hard-to-Treat ovarian cancers
NCT ID NCT06469281
First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 29 times
Summary
This early-stage study tests an experimental treatment called 27T51, a type of immune cell therapy (CAR T) designed to target a protein called MUC16 found on certain cancer cells. The study involves about 90 women with ovarian, peritoneal, or fallopian tube cancer that has come back or is hard to treat. The goal is to check if the therapy is safe and to find the best dose, with some participants also receiving other medications alongside 27T51.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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John Theurer Cancer Center Hackensack University Medical Center
RECRUITINGHackensack, New Jersey, 07601, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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LDS Hospital
RECRUITINGSalt Lake City, Utah, 84143, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
Contact Phone: •••-•••-••••
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Roswell Park Cancer Institute
RECRUITINGBuffalo, New York, 14203, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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UPMC Hillman Cancer Center
RECRUITINGPittsburgh, Pennsylvania, 15232, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.