Could 24 hours of antibiotics be enough before urological surgery?
NCT ID NCT07206992
First seen Jun 27, 2026 · Last updated Aug 21, 2026 · Updated 2 times
Summary
This study looks at whether giving antibiotics for just 24 hours before urological surgery works as well as the usual 48-hour course to prevent infections after the procedure. About 894 adults with a positive urine culture who are scheduled for certain types of urological endoscopic surgery will take part. The goal is to see if a shorter antibiotic course can safely reduce the risk of post-operative infections.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 894 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Oct 2026
An estimate. Start dates often move.
- Expected to finish
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Nov 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Male participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients over 18 years of age * Patients scheduled for urological endoscopy for one of the following indications: endoscopic surgery of the upper urinary tract (diagnostic, for treatment of stones or ureteral strictures), endoscopic prostate surgery (with or without laser: enucleation, vaporisation, resection), endoscopic surgery of the bladder and urethra (particularly tumours, strictures and foreign bodies) and ureteral stent surgery * Patients with a positive preoperative urine culture (presence of bacteria at more than 103/mL) * Asymptomatic patients (no signs of urinary tract infection in particular) * Patients affiliated with or covered by a social security scheme * French-speaking patients who have signed an informed consent form Exclusion Criteria: * Patient participating in another clinical trial * Protected patient: adult under guardianship, curatorship or other legal protection, deprived of liberty by judicial or administrative decision * Patient with an immune deficiency * Patient presenting symptoms of preoperative pyelonephritis (fever)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hôpital Privé des Peupliers
Paris, 75013, France
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Other studies related to the condition(s) this trial covers.
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