Can a natural compound fix 'good' cholesterol in genetic heart disease?
NCT ID NCT04941599
First seen Nov 06, 2025 · Last updated May 24, 2026 · Updated 26 times
Summary
This study tests whether a supplement called 2-HOBA can improve the function of HDL (good cholesterol) in people with familial hypercholesterolemia, a genetic condition that causes very high cholesterol and heart disease risk. Researchers will give 72 participants either 2-HOBA or a placebo for 6 weeks and measure changes in cholesterol function. The goal is to see if 2-HOBA can reduce harmful modifications to cholesterol particles.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Vanderbilt University Medical Center
RECRUITINGNashville, Tennessee, 37212, United States
Conditions
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