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Bigger IV, same pain? new study challenges old belief

NCT ID NCT07629427

Symptom relief Sponsor: Marmara University Pendik Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 06, 2026 · Updated 2 times

Summary

This study compares two sizes of IV cannulas (18-gauge vs 20-gauge) in emergency patients to see if the larger one causes more pain or is harder to insert. About 204 adults with low-to-moderate difficulty for IV access will be randomly assigned to one size. Patients will wear goggles so they don't know which size they get. The goal is to find out if the larger cannula, which can deliver fluids faster, is as comfortable as the smaller one.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
peripheral intravenous cannula (18-gauge or 20-gauge)
What this could lead to
If larger cannulas cause no more pain, emergency staff may use them more often, improving care for patients who need fast fluids or contrast.
What could go wrong
This is a small, single-center study. Results may not apply to all patients or settings. Pain is subjective and hard to measure precisely.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

204 people

The number who actually took part.

Started

Jul 2026

Finished

Aug 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 18 years of age or older * Requiring intravenous access for diagnostic or therapeutic purposes * Classified as low or moderate risk according to the A-DIVA (Adult Difficult Intravenous Access) score * Provision of informed consent by the patient, a relative, or a legal guardian Exclusion Criteria: * Inability to effectively communicate pain intensity due to cognitive impairment, altered mental status, or visual or language difficulties * Hemodynamic instability defined as systolic blood pressure less than 90 mmHg or mean arterial pressure less than 65 mmHg

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Conditions

The condition(s) this trial relates to.

Pain vein disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Emergency department patient Pain Peripheral catheterization Procedural difficulty VEINS

Contacts and locations

Locations

  • Marmara University Pendik Training and Research Hospital

    Istanbul, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.