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New radiation therapy targets hard-to-treat prostate cancer

NCT ID NCT05413850

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 32 times

Summary

This study tests a new drug called 177Lu-rhPSMA-10.1 in men with metastatic castrate-resistant prostate cancer, a type of prostate cancer that has spread and no longer responds to hormone therapy. The drug delivers radiation directly to cancer cells. The study has two phases: Phase 1 checks safety and the right dose, and Phase 2 measures how well it shrinks tumors or lowers PSA levels. About 82 men will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beatson West of Scotland Cancer Center

    RECRUITING

    Glasgow, G12 0YN, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Biogenix Molecular LLC

    RECRUITING

    Miami, Florida, 33165, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Bristol Hematology and Oncology Center

    RECRUITING

    Bristol, BS2 8ED, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Emory University Hospital

    RECRUITING

    Atlanta, Georgia, 30322, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Rechts der Isar

    RECRUITING

    Munich, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • James Cook University Hospital

    RECRUITING

    Middlesbrough, TS4 3BW, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Meander Medisch Centrum

    RECRUITING

    Amersfoort, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • NovaCure Health

    RECRUITING

    Miami, Florida, 33176, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Oxford University Hospitals NHS Foundation Trust

    RECRUITING

    Oxford, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Radboud UMC

    RECRUITING

    Nijmegen, Gelderland, 6525GA, Netherlands

    Contact Email: •••••@•••••

  • Saint Luc University Hospital

    RECRUITING

    Brussels, 1200, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • St Bartholomew's Hospital

    RECRUITING

    London, EC1A 7BE, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital Aachen

    RECRUITING

    Aachen, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital Essen

    RECRUITING

    Essen, Germany

    Contact Email: •••••@•••••

  • University Hospital Ghent

    RECRUITING

    Ghent, 9000, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital Leuven

    RECRUITING

    Leuven, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital Southampton NHS Foundation Trust

    RECRUITING

    Southampton, SO16 6YD, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Universitätsklinikum Augsburg

    RECRUITING

    Augsburg, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Weill Cornell Medicine - New York - Presbyterian Hospital

    COMPLETED

    New York, New York, 10065, United States

  • Weston Park

    RECRUITING

    Sheffield, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • XCancer Omaha / Urology Cancer Center

    RECRUITING

    Omaha, Nebraska, 68130, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.