Vall D'hebron Institute Of Oncology

This study tests whether giving a combination of three drugs (pembrolizumab, belzutifan, and lenvatinib) before surgery can shrink kidney tumors in people with localized clear cell renal cell carcinoma. About 150 participants will receive the drugs for 12 weeks, then have surgery…

This study tests whether giving a second round of two drugs (encorafenib and cetuximab) can help control advanced colorectal cancer with a specific BRAF mutation. About 25 adults who have already tried other treatments will receive the drugs until their cancer worsens or side eff…